Fang Fang
Ph.D, Principle Investigator

Research interest :

Stem cell biology

Transcriptional regulation and cell fate decision

Human reproductive biology and development

Disease modeling of neurodegenerative diseases

Education and Appointment :

2019-Present: Research Professor, University of Science and Technology of China

2014-2019 Research Scientist, Department of Cell Biology and Neuroscience, Montana State University

2011-2014 Postdoctoral fellow, Institute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine

2006-2011 Ph.D. in Computation and Systems Biology, Singapore-Massachusetts Institute of Technology (MIT) Alliance, National University of Singapore

2004-2006 Master of Science in Microbiology, College of Life Science, Wuhan University, China

2000-2004 Bachelor of Science in Biotechnology, College of Life Science, Wuhan University, China

Contact : ffang24@ustc.edu.cn

Ninuo Xia, Ph.D

Research interest :

Stem cell biology

Transcriptional regulation and cell fate decision

Disease modeling of neurodegenerative diseases

mRNA biology

Education and Appointment :

2019-Present: Associate Research Professor, University of Science and Technology of China

2014-2019 Research Scientist, Department of Cell Biology and Neuroscience, Montana State University

2010-2014 Postdoctoral fellow, Institute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine

2003-2009 Ph.D. in Biochemistry, University of California, Riverside

1998-2002 Bachelor in Biochemistry, Peking University

Contact : nxia007@ustc.edu.cn

Lingling Zhu,Ph.D

Job title : Post-Doctors
Biography : Dr. Zhu was graduated from Sichuan University in 2020.
Representative : Publication

Lingling Zhu*, Yujia Yuan*, Longhui Yuan, Lan Li, Fei Liu, Jingping Liu, Younan Chen, Yanrong Lu and Jingqiu Cheng . Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury. Theranostics. 2020.

Yingang Wu,M.D.,Ph.D.

Job title : Attending physician of neurosurgery
Research interests : traumatic brain injury associated bleeding abnormalities
Biography :

Dr.Wu was graduated from Tianjin Medical University in 2018. During his doctoral degree, he was sponsored by the China Scholarship Council to study as a joint PhD student in the University of Washington from 2016 to 2018.

Representative Publication :

Yingang Wu, Wei Liu, Yuan Zhou, Tristan Hilton, Zilong Zhao, Wei Liu, Min Wang, Jason Yeon, Katie Houck, Perumal Thiagarajan, Fangyi Zhang, Fu-Dong Shi, Xiaoping Wu, Min Li, Jing-fei Dong, Jianning Zhang. von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury. Blood. 2018,132(10):1075-1084.

Xueting Xu, Ph.D.

Job title : Special Associate Research Professor
Major : Cell biology
Research interest : Stem cell fate transition
Education and Appointment :

2025-Present: Special Associate Research Professor, University of Science and Technology of China;

2022-2024: Post-Ph.D, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences;

2015-2022: Ph.D in Cell biology, University of Science and Technology of China;

2011-2015: Bachelor in biotechnology, Anhui university.

Representative Publication :

Li P, Xu S, Wu X, Gao Y, Tanveer Ahmed, Huang Y, Qin Q, Qin B, Wang L, Xu X. Hyperactivation of mTORC1 blocks stem cell fate transitions through TFE3-NuRD association. EMBO Rep.

Xu X, Ahmed T, Wang L, Cao X, Zhang Z, Wang M, Lv Y, Kanwal S, Tariq M, Lin R, Zhang H, Huang Y, Peng H, Lin D, Shi X, Geng D, Liu B, Zhang X, Yi W, Qin Y, Esteban MA, Qin B. The mTORC1-eIF4F axis controls paused pluripotency. EMBO Rep. 2022 Feb 3;23(2): e53081.

Xu X, Qin B. Pausing pluripotency via RNA methylation. Nat Cell Biol. 2023 Sep;25(9): 1241-1242.

Wang L, Xu X, Jiang C, Ma G, Huang Y, Zhang H, Lai Y, Wang M, Ahmed T, Lin R, Guo W, Luo Z, Li W, Zhang M, Ward C, Qian M, Liu B, Esteban MA, Qin B. mTORC1-PGC1 axis regulates mitochondrial remodeling during reprogramming. FEBS J. 2020 Jan;287(1): 108-121.

Contact : xuxt@ustc.edu.cn

Junjie Tang, Ph.D.

Postdoctoral Fellow, School of Life Science and Medicine, University of Science and Technology of China (USTC)

Doctoral Degree : Biomedical Engineering

I specialize in cutting-edge, interdisciplinary research spanning biomaterials, targeted nanoparticles, multifunctional hydrogels, stem-cell delivery systems, and tissue repair. My particular expertise lies in engineering multifunctional hydrogels for tissue regeneration and wound healing, where I have built a solid scientific foundation and a proven record of innovation. To date, I have authored 32 high-impact peer-reviewed articles in leading journals such as Biomaterials, ACS Nano, Bioactive Materials, Acta Biomaterialia, and Exploration, with total citations exceeding 1,000.

Personal interests : badminton, hiking, and fishing.
Contact : tangjunjie0909@ustc.edu.cn
Research Article :

Junjie Tang, Penglei Zhang, Yadong Liu, Dingyu Hou, You Chen, Lili Cheng, Yifang Xue,Jie Liu, Revolutionizing pressure ulcer regeneration: Unleashing the potential of extracellular matrix-derived temperature-sensitive injectable antioxidant hydrogel for superior stem cell therapy, Biomaterials(Q1,14.0), 314 (2025) 122880.

Junjie Tang, Yadong Liu, Yifan Xue, Zhaozhong Jiang, Baizhu Chen, Jie Liu, Endoperoxide‐enhanced self‐assembled ROS producer as intracellular prodrugs for tumor chemotherapy and chemodynamic therapy, Exploration(Q1,22.5), 20230127.

Junjie Tang, Xiaoge Zhang, Lili Cheng, Yadong Liu, You Chen, Zhaozhong Jiang, Jie Liu, Multiple stimuli-responsive nanosystem for potent, ROS-amplifying, chemo-sonodynamic antitumor therapy, Bioactive Materials(Q1,20.3), 15 (2022) 355-371.

Man Shu#, Junjie Tang#, Lili Chen, Qiang Zeng, Chao Li, Shuting Xiao, Zhaozhong Jiang, Jie Liu, Tumor microenvironment triple-responsive nanoparticles enable enhanced tumor penetration and synergetic chemo-photodynamic therapy, Biomaterials(Q1,14.0), 268 (2021) 120574.

Penglei Zhang#, Junjie Tang#, Lili Cheng, Yifan Xue, Jiahuan Yang, Zhongsheng Sun, Jie Liu*, Hyaluronic acid modified liposomes with enhanced transdermal delivery of methotrexate for psoriasis treatment, Colloids and Surfaces B: Biointerfaces (Q1,5.6), 247,2025,114457

Mingye chen#, Junjie Tang#,Binfa Liang, Gang Feng, Zefeng Deng, Simin Chen, Qing Sun, Jie Liu, Xian Chen, Acta Biomaterialia (Q1,9.6),207(2025) 264-280

Minpeng Huang,Graduate student

Minpeng Huang,Graduate Student
Cell Biology, University of Science and Technology of China
Research Interests:stem cell senescence,Stem cell directed differentiation
Email:hmp1996@mail.ustc.edu.cn

Lei Liu,Graduate student

I'm Liu Lei and I was graduated from Shangqiu Normal University.My major is biotechnology.And I got my bachelor degree after my graduation in the year of 2019. I have two hobbies that help people have a healthy body and mind. By doing stem cells, I hope to make a contribution to human health. And Chinese sinology, such as Tai Chi culture, can purify one's mind.

Lei Diao,Graduate student

Lei Diao(刁蕾),Graduate Student.
B.S: Biotechnology, Inner Mongolia University
Research Interests: Stem cell directed differentiation to treat infertility.
Email:1220698226@qq.com

Qian Dai,Lab Manager

Pomology,Huazhong Agricultural University
Job Description:Daily Management
Email:1343638404@qq.com

Visiting Students/Interns

YanYan Gao ,Jiangxi Medical College
Department of laboratory medicine, Anhui Tianlun infertility hospital
Research Interests: Medical Laboratory

Kai Chen. Graduate Student

B.S: Clinical Medicine, Wannan Medical College.
Research Interests: Reproductive Medicine.
Email:20209442@wnmc.edu.cn

Xunliang Li. Graduate Student

B.S: Clinical Medicine, Wannan Medical College.
Research Interests:Perinatal Medicine.
Email:20209444@wnmc.edu.cn

Yidan Wang. Graduate Student

B.S: Biology Science, Northwest University.
Research Interests: Treat disease by stem cell.
Email:631760193@qq.com

Huiru Wang. Graduate Student

B.S: Clinical Medicine, Changzhi Medical College.
Research Interests: Reproductive Medicine.
Email:342905580@qq.com

Xin Zhao. Graduate Student

B.S:Clinical Medicine,Wannan Medical College.
Research Interests:Reproductive Medicin.
Email:zx322yxs@163.com

Hui MA,Granduate Student

B.S: Animal Pharmacy, Nanjing Agricultural University.
Research Interests: Reproductive Medicine.
Email:632802614@qq.com

Zhao Nuannuan,Graduate student

B.S: Ecology, Anhui Normal University
Research Interests: Stem cell directed differentiation.
Email:769528128@qq.com

Faqi Li, Graduate student

Graduated from USTC with a major in biotechnology. I love tokusatsu, especially the Ultraman and Masked Rider series. Other than that, my hobbies include anime, basketball and guitar. I am passionate and hopeful about stem cell medicine and hope to realize my dream for the benefit of all mankind.

Xiaoyan Zhong,Graduate Student.

Biology and Medicine, University of Science and Technology of China.

Research interest : Stem cell induction and differentiation.
Contact : zxy233@mail.ustc.edu.cn

Fang Lixuan, Graduate Student.

Biotechnology, Graduate Student at USTC.

Enjoys basketball, esports, and traveling.