Publications

1. Fang F, Iaquinta PJ, Xia N, Liu L, Diao L, Reijo Pera RA#. Transcriptional control of human gametogenesis. Human Reproduction Update (2022) https://doi.org/10.1093/humupd/dmac002.

2. Liu L, Fang F#. Long noncoding RNA mediated regulation in human embryogenesis, pluripotency, and reproduction. Stem Cells International (2022). https://doi.org/10.1155/2022/8051717

3. Xia N, Cabin D, Fang F#, Reijo Pera RA#. Parkinson’s Disease: Overview of transcription factor regulation, genetics, and cellular and animal models（2022）. Frontiers in Neuroscience. DOI:10.3389/fnins.2022.894620

4. Diao L, Turek PJ, John CM, Fang F#, Reijo Pera RA#. Roles of sermatogonial stem cells in spermatogenesis and fertility restoration. Frontiers in Endocrinology (2022) May 12; 13:895528. DOI:10.3389/fendo.2022.895528

5. Zheng S, Gao Y, Chen K, Liu Y, Xia N#, Fang F#. A Robust and Highly Efficient Approach for Isolation of Mesenchymal Stem Cells from Wharton’s Jelly for Tissue Repair. Cell Transplantation (2022). DOI:10.21203/rs.3.rs-882696/v1

6. Fang F*, Angulo B, Xia N, Sukhwani M, Wang Z, Carey CC, Mazurie A, Cui J, Wilkinson R, Wiedenheft B, Surani AM, Orwig KE, Reijo Pera RA. A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells. Nature Cell Biology 20，655-665 (2018). Cover paper on the issue.

7. Fang F#*, Xia N#, Angulo B, Carey J, Durruthy-Durruthy J, Sebastiano V, Bennett T, Reijo Pera RA. A distinct isoform of ZNF207 controls self-renewal and pluripotency of human embryonic stem cells in conjunction with master transcription factors. Nature Communications 9, 4384 (2018). Editors’ Highlight paper.

8. Xia N#*, Fang F#, Zhang P#, Cui J, Tep-Cullison C, Hamerley T, Lee HJ, Palmer T, Bothner B, Lee HJ, Reijo Pera RA. A Knock-In Reporter allows purification and characterization of mDA neurons from heterogeneous populations. Cell Reports. 18(10):2533-2546 (2017).

9. Xia N#, Zhang, P#, Fang, F#, Wang Z, Rothstein M, Augulo B, Chiang R, Taylor J, Reijo Pera RA. Transcriptional comparison of human induced and primary midbrain dopaminergic neurons. Scientific Reports. 6, 20270 (2016).

10. Cui J, Rothstein M, Bennett T, Zhang P, Xia N, Reijo Pera RA. Quantification of dopaminergic neuron differentiation and neurotoxicity via a genetic reporter. Scientific Reports. 6:25181(2016).

11. Ramathal C, Angulo B, Sukhwani M, Cui J, Durruthy Durruthy J, Fang F, Schanes P, Turek PJ, Orwig KE and Reijo Pera RA. DDX3Y gene rescue of a Y chromosome AZFa deletion restores germ cell formation and transcriptional programs. Scientific Reports. 15041(2015).

12. Fang F*#, Xu Y*, Chen X, Ng HH#, Matsudaira, P. Coactivators p300/CBP regulate self-renewal in embryonic stem cells by mediating long-range chromatin structure. Stem Cells. 32(7):1805-16 (2014).

13. Xia N, Zhang P, Reijo Pera RA. (2014) Directed differentiation of dopaminergic neurons from human pluripotent stem cells. J Vis Exp. (91)51737(2014).

14. Durruthy-Durruthy J, Ramathal C, Sukhwani M, Fang F, Cui J, Orwig KE, Reijo Pera RA. Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. Human Molecular GeneticsHuman Molecular Genetics. 23, 3071-84 (2014).

15. Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW…Fang F…. Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in theCLARITY Challenge. Genome Biology. 15(3): R53 (2014)

16. Xie D, Chen CC, Ptaszek LM, Xiao S, Cao X, Fang F, Ng HH, Lewin HA, Cowan C, Zhong S. Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species. Genome Research. 20(6):804-15 (2010).

17. Hong F, Fang F, He X, Cao X, Chipperfield H, Xie D, Wong WH, Ng HH, Zhong S. Dissecting early differentially expressed genes in a mixture of differentiating embryonic stem cells. PLoS Computational Biology. 5(12): e1000607 (2009).

18. He X, Chen CC, Hong F, Fang F, Sinha S, Ng HH, Zhong S. A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data. PLoS One. 4(12): e8155 (2009).

19. Chen X#, Xu H#, Yuan P, Fang F, Huss M, Vega VB, Wong E, Orlov YL, Zhang W, Jiang J, Loh YH, Yeo HC, Yeo ZX, Narang V, Govindarajan KR, Leong B, Shahab A, Ruan Y, Bourque G, Sung WK, Clarke ND, Wei CL, Ng HH. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell. 133, 1106-1117 (2008).

20. Chen X#, Fang F#, Liou YC, Ng HH. Zfp143 regulates Nanog through modulation of Oct4 binding. Stem Cells. 26(11):2759-67 (2008).